Department of biotechnology, Government of India has provided great impetus in the form of infrastructure and human resource. The states in south and Maharashtra have utilized biotechnology in health care and agriculture and have attracted investment from a number of biotech industries from country and abroad. Bengaluru is considered as the most developed biotech city in the country and is followed by Mumbai/Pune belt and Hyderabad.
U.P., however, has not been able to apply biotechnology for its development, though significant expertise in terms of R&D institutions,Human resource and agricultural diversity exists.

Agriculture sector in U.P. has made significant progress. it is first amongst state in the production of wheat(25.9 million ton, 35% of total production in the country).The state ranks second in the production of sugarcane(122 million tons,40%),fruits(8.5 million ton,18%),potatoes(38%) and milk(12.9 million ton).Food production yield of the state is higher than the international levels of yield.
The state used about 2.5 million ton (22%) of nitrogenous fertilizers, 0.55 million ton (16%) of phosphatic fertilizers in 1998-99. The bias for nitrogen in an unbalanced use of fertilizer is obvious.

In spite of such consumption the productivity of crops is low. There is large gap between potential and actual yield of most crops. The state has not been able to do much in the health, dairy and food sectors In spite of resources. Through application of tissue culture productivity of horticulture, Floriculture and agriculture can be enhanced and made economically beneficial. With the application of these areas it would be possible to enhance the productivity of food, milk and induce health care through nutraceuticals and pharmaceuticals. Lucknow offers a multidisciplinary blend of excellent facilities and expertise in the area of biotechnology. Around 3000highly qualified scientists are working in four CSIR laboratories and three ICR laboratories in the city and many of them have earned national and international recognition. These institutes have excellent expertise in the area of biomedical sciences and drug development, toxicology and environmental protection, production of past resistant plants, high yield crop and fruit varieties.

Realizing the great potential of U.P., Lucknow has been declared as Biotechnology City of India during the 89th session of the Indian Science Congress at January 3, 2002.A biotechnology park with the sponsorship of department of biotechnology,Govt. of India and the collaboration with Department of Science and Technology,U. P. Govt.,CSIR and other agencies is being setup at Kursi Road Jankipuram ,Lucknow on 8 acres of land proposed by the Department of science and technology, UP Govt. In order to provide forward linkages of the park biotech Networking Facilities will be developed by Council of science & technology, U.P. at agriculture farm Of about 28 acres of U.P. State Institute of Rural development, Bakshi Ka Talab, Lucknow.also, an area of about 200 acres have been identified for setting up of Biotech Industries on Lucknow-Kanpur road near Amausi AIR port. This will be developed by UPSIDC as biotech Industrial Park.

To harness benefits of biotechnology for the prosperity of the state, the govt .of U.P. has charted a Biotech policy. The state would encourage growth of manpower and resources in key areas like bioinformatics, plant and animal genetics by networking with the existing institutions, universities and medical institutes. it would also set up Centres for excellence in human genetics, applied biotechnology, transgenic plants and animals, safety evaluation of biotech products. The state would develop institutional mechanism to carry the fruits of Biotech R&D being pursued at research institutions and technology incubators of the Biotech park to farmers for employment generation through tissue culture and macro-propagation. It would provide better quality and high yielding variety of crops and plants to farmers.